Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

Jun.30.2025
Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”
Alan Zhao, CEO of 2Firsts, calls on the global tobacco harm reduction community to “emancipate the mind and seek truth from facts,” rebuild scientific consensus, and drive high-quality development.

This article reflects the views of the author only.

 


 

In mid-June, the Global Forum on Nicotine (GFN) took place in Warsaw. As one of the most prominent platforms for dialogue on tobacco harm reduction (THR), this year’s event gathered scientists, researchers, media representatives, and senior executives from around the world to discuss and explore major challenges and opportunities in THR.

 

For the third consecutive year, 2Firsts served as a media partner of GFN, conducting pre-event interviews and on-site reporting. We published several key interviews and feature articles (see links below).

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”
Alan Zhao was invited to give a keynote video address at the 2023 Global Forum on Nicotine.| Image: 2Firsts

 

Just a month earlier, ahead of World No Tobacco Day, 2Firsts interviewed several global tobacco control experts, including Dr. Derek Yach, former Executive Director of the WHO, and Mr. Samrat Chowdhery, Director of the Association of Vapers India. They shared perspectives on global tobacco control trends as well as country-specific case studies on harm reduction.

 

Looking back on these interviews and reports, I found that these experts, despite coming from different regions and backgrounds, all expressed a common concern: a widening gap in the global understanding of tobacco harm reduction. Among scientists, industry leaders, policymakers, and tobacco control advocates, the divisions over how to address tobacco use and seize the opportunities and challenges of harm reduction have never been so stark.

 

I also recalled that just a few months ago, a health official from a Southeast Asian country publicly claimed that there was no evidence proving e-cigarettes are less harmful than traditional tobacco products, even suggesting that e-cigarettes might be more harmful than cigarettes.

 

How can such profound differences in perception exist on an issue that affects the lives and health of tens of millions of people worldwide? I don’t have a definitive answer. However, after listening to many experts, I am more convinced than ever that global tobacco control and harm reduction efforts require a deep transformation of thinking.

 

A famous Chinese statesman once put forward the principle of “emancipating the mind and seeking truth from facts,” which directly inspired China’s historic reform and opening-up that began in the late 1970s.

 

Today, the global THR community—across science, industry, and policy—needs to rebuild a cooperative framework based on scientific consensus, uphold long-term thinking, and redefine harm reduction concepts and strategies. We must also fully embrace the possibilities offered by new technologies in reducing harm.

 

In this process, 2Firsts, as an industry-focused media platform, has an increasingly clear mission and value: to serve as a bridge connecting science, industry, regulators, and society; to promote the broad dissemination of facts and ideas; and to help drive the high-quality development of global tobacco harm reduction efforts.

 

Alan Zhao

Co-founder & CEO, 2Firsts

 


 

2Firsts Global Nicotine Forum 2025 Coverage Series

 

1.2FIRSTS | GFN Experts Warn: Misinformation is Killing Smokers

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

2.2FIRSTS | Tobacco Giants Speak on THR at GFN: Calling for Regulatory Reform Aligned with Scientific Understanding

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

3. 2FIRSTS | Dialogue Over Dogma: GFN Co-founder Paddy Costall Lauds Diversity of Voices at 2025 Event

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

4.2Firsts Talks with Nancy Loucas, Asia-Pacific THR Leader: Giving a Voice to the Overlooked Consumer

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

5.2Firsts Interviews Harm Reduction Policy Expert Jeannie Cameron: WHO’s Rejection of Harm Reduction Is Undermining Global Tobacco Control

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

 

2Firsts World No Tobacco Day 2025 Series

 

1.World No Tobacco Day 2025: Former WHO Executive Director Dr. Derek Yach Calls for Embracing Harm Reduction — A 2Firsts Exclusive

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

2.2FIRSTS | World No Tobacco Day 2025: Former WHO Executive Director Dr. Derek Yach Calls for Embracing Harm Reduction — A 2Firsts Exclusive

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

3.India’s Vape Ban: A Case Study in Unintended Consequences | By Association of Vapers India Director for 2Firsts

 

India’s Vape Ban: A Case Study in Unintended Consequences | By Association of Vapers India Director for 2Firsts

 

4.2FIRSTS | Indian Tobacco Control Expert Contributes to 2Firsts: Understanding India’s Smokeless Landscape

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 

5.Five Key Takeaways from the E-Cigarette Regulatory Press Conference: Stricter Oversight, Production Control, and Crackdown on Grey Market — In-Depth Analysis by 2Firsts’ Alan Zhao on Policy Logic and Industry Impact

 

Alan Zhao, 2Firsts: The Global Tobacco Harm Reduction Community Urgently Needs to “Emancipate the Mind and Seek Truth from Facts”

 


Welcome to submit articles, contact for interviews, or provide comments to 2Firsts. Please contact: info@2firsts.com, or connect with 2Firsts CEO Alan Zhao on LinkedIn.

 

 

FDA Proposes Foreign Tobacco Factory Registration Rule to Tighten Import Oversight
FDA Proposes Foreign Tobacco Factory Registration Rule to Tighten Import Oversight
The FDA has proposed a rule requiring foreign tobacco manufacturers to register facilities and list products before exporting to the U.S. If finalized, the rule could affect overseas OEM/ODM factories, contract manufacturers, specification developers, bulk product makers, and repackaging or relabeling firms. FDA says the proposal would help identify unauthorized imported tobacco products, including e-cigarettes.
Special Report
Jun.26
Altria Reports Q1 2026 Net Revenues of $5.43 Billion and 7.3% Growth in Adjusted Diluted EPS
Altria Reports Q1 2026 Net Revenues of $5.43 Billion and 7.3% Growth in Adjusted Diluted EPS
Altria Group reported its first-quarter 2026 results on April 30. Net revenues were $5.43 billion, up 3.2% year on year, while revenues net of excise taxes were $4.76 billion, up 5.3%. Reported diluted EPS was $1.30, up more than 100%, and adjusted diluted EPS was $1.32, up 7.3%.
May.06 by 2FIRSTS.ai
Malaysia Police Plan Saliva Tests at Roadblocks to Detect Synthetic Drugs Mixed Into Vape Liquids
Malaysia Police Plan Saliva Tests at Roadblocks to Detect Synthetic Drugs Mixed Into Vape Liquids
Malaysian police plan to use saliva test kits at roadblocks to detect drivers using synthetic liquid drugs marketed as “Piu Piu” and “Magic Mushroom,” substances that authorities say are mixed into vape liquids and inhaled through e-cigarette devices, raising road-safety concerns and adding pressure on vape regulation.
Jun.29
Reuters: Big Tobacco Emerges as Winner After FDA Regulatory Shift
Reuters: Big Tobacco Emerges as Winner After FDA Regulatory Shift
According to Reuters, major tobacco companies may emerge as key beneficiaries after the U.S. FDA loosened regulations on vaping and nicotine pouch products, a shift that has sparked debate over public health risks.
Industry Insight
May.26
Malaysian Court Rules Liquid Nicotine Exemption Irrational, Renewing Vape Regulation Debate
Malaysian Court Rules Liquid Nicotine Exemption Irrational, Renewing Vape Regulation Debate
Malaysia’s High Court ruled that the government’s earlier decision to remove liquid nicotine from the country’s Poisons List was “irrational,” reigniting debate over vape regulation, illicit trade, and youth protection.
Regulations
May.18
2Firsts Hosts U.S. Compliance Briefing on Building PMTA Support Capabilities Across the Nicotine Supply Chain
2Firsts Hosts U.S. Compliance Briefing on Building PMTA Support Capabilities Across the Nicotine Supply Chain
2Firsts held a U.S. compliance briefing in Shenzhen to help vaping, heated tobacco and nicotine pouch supply chain companies strengthen PMTA support capabilities. The event focused on supplier documentation, quality systems, traceability, TPMF/TPMP pathways, age verification and customer audit readiness as U.S. compliance expectations increasingly extend deeper into the nicotine supply chain.
Events
Jun.12